The development and spread of antibiotic resistance represents one of the greatest threats to global health. To overcome these resistances, drugs with novel modes of action are urgently needed.

Scientists from the University of Illinois Urbana-Champaign have developed a method to isolate genes from amounts of microbial DNA so tiny that it would take 20,000 samples to weigh as much as a ...

Advanced microscopy techniques give scientists valuable clues for how to fight an enzyme that is leading to a rise in cases of antibiotic-resistant bacterial infections worldwide. Bacteria draw from ...

As more and more bacteria develop resistance to the drugs designed to kill them, a new study has found that even a relatively new antibiotic isn’t immune. Researchers have uncovered a gene ...

Researchers have combined the bacteria-killing actions of two classes of antibiotics into one, demonstrating that their new dual-action antibiotic could make bacterial resistance (almost) an ...

A new antibiotic that works by disrupting two different cellular targets would make it 100 million times more difficult for bacteria to evolve resistance, according to new research from the University ...

A new analysis shows that infectious bacteria exposed to the antibiotic albicidin rapidly develop up to a 1,000-fold increase in resistance via a gene amplification mechanism. A new analysis shows ...

As more and more pathogenic bacteria gain resistance to commonly used antibiotics, the search for new, effective, and safe antibiotics has become vital. According to The Lancet, almost 5 million ...

Bacteria draw from an arsenal of weapons to combat the drugs intended to kill them. Among the most prevalent of these weapons are ribosome-modifying enzymes. These enzymes are growing increasingly ...