Tumor-infiltrating clonal hematopoiesis increased the risk of disease recurrence or death among patients with cancer. TET2 mutations were the strongest genetic predictor of tumor-infiltrating clonal ...

Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related condition associated with increased mortality among patients with cancer. CHIP mutations with high variant-allele frequencies ...

Clonal hematopoiesis is the expansion of a genetically related population of hematopoietic stem and progenitor cells that disproportionately contribute to blood-cell production. 1 Clonal hematopoiesis ...

Hyperthermic Intraperitoneal Chemotherapy in Platinum-Sensitive Recurrent Ovarian Cancer: A Randomized Trial on Survival Evaluation (HORSE; MITO-18) Clonal hematopoiesis (CH) has been associated with ...

Serial circulating tumor DNA analysis can demonstrate rapid clonal dynamics that evolve during response and resistance to both standard chemotherapy and targeted therapy of BRAF-mutant colon cancer ...

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All cells within the same cancer are not the same. They all have genetic errors that turn them into tumor cells, but these errors are not identical. In each cancer, there are populations of cells with ...

About 1 in 5 patients with cancer who undergo genetic testing are incidentally found to have mutations in their blood called clonal hematopoiesis of indeterminate potential (CHIP). A study from ...

A study unveils a newly constructed immune map, highlighting the distinct immune infiltrate patterns in pancreatic tumors. These findings could pave the way for tailored immunotherapies and improved ...

Tumor-infiltrating clonal hematopoiesis (TI-CH) increased the risk of disease recurrence or death among patients with early non-small cell lung cancer (NSCLC), and the risk of death from any cause ...