Figure 1: Cryo-EM of dimeric dynein motors bound to MTs in 2 mM Mg-ATP. The structural basis of processive stepping by cytoplasmic dynein has not previously been investigated. Understanding of ...
The motor protein dynein is predicted to move the tail domain, a slender rod-like structure, relative to the catalytic head domain to carry out its power stroke. Here, we investigated ATP hydrolysis ...