Constructed with tubulin heterodimers connected into a hollow cylinder, the microtubule, an essential component of the cytoskeleton, plays a vital role in various intracellular processes. In a recent ...
A Northwestern Medicine study has shed light on one of the most intricate construction projects in biology: how cells build ...
Direct evidence that microtubules function as mechano-sensors and regulate the intracellular transport of molecules has been reported, leading to new possibilities in the fields of biomechanics, ...
As organisms grow, live, and move through the world, they're subjected to an array of internal and external forces. Biological forms must be able to withstand the stresses of stretching and ...
Representative kymographs showing single GFP-tagged ATAT-2 molecules on GMPCPP-stabilized MEC-12/MEC-7 (left) and TBA-2/TBB-2 (right ...
For the first time, researchers have directly visualized how newly formed cellular organelles leave the endoplasmic reticulum ...
Clumps and tangles of tau protein are associated with Alzheimer's disease and other dementias, but tau protein also plays a role in healthy nerve cells. Healthy tau can assemble into an envelope ...
Studies have shown that in ALS patients, microtubules—which are the major component of the cell cytoskeleton and serve as tracks for transporting components from cell bodies to neuronal ...
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Dual targeting strategy suppresses pancreatic cancer cell growth
A new research paper was published in Volume 13 of Oncoscience on January 28, 2026, titled "Dual targeting of oncogenic ...
Each cell in your body is an incredibly complicated piece of machinery, and we only know the outlines of how they work. If a cell were a car, we’d understand the details for, say, the steering wheel ...
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