Large-conductance calcium-activated potassium (BK) channels are critical determinants of smooth muscle function by mediating rapid feedback between intracellular calcium levels and membrane potential.
DeGolier's research interests include smooth muscle physiology and pharmacology in vitro, peptide regulation of gastrointestinal, uterine, and vascular smooth muscle motility, and the use of herbs in ...
School of Medicine scientist receives continued funding to support smooth muscle plasticity research
Kenton Sanders, Ph.D., chair of the physiology and cell biology department at the University of Nevada School of Medicine, has received Phase 3 funding in the amount of $5.4 million over the next five ...
The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...
Danielle “Nellie” Bruns, an associate professor in the University of Wyoming’s Department of Zoology and Physiology, has received a five-year, $1.78 million research grant from the National Institutes ...
Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...
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