Combination therapy led to complete remission in more than 50% of mice with different tumor types, many of which were resistant to ICB therapy alone.

Speaking at the ELRIG meeting at Hinxton Hall in March, Dr Seng H. Cheng set out how next-generation adeno-associated viral ...

A key cancer-fighting gene in leukemia is switched off—not broken—and scientists from The Jackson Laboratory (JAX) have found a way to switch it back on. In a study published in Science Translational ...

A new tool that uses machine learning for drug discovery predicts how molecules will influence gene expression.

The study challenges the notion of a “one-size-fits-all” mechanism in bacterial transcription and highlights the diversity of regulatory strategies employed by pathogens.

Researchers have mapped how "histone bivalency" acts as a molecular clock for brain development. By holding genes in a poised state, this mechanism ensures neurons mature only after completing ...

Like tiny superheroes, small, naturally occurring segments of RNA can block multiple molecular paths that cancer cells use to ...

GARDian3 trial enrollment and dosing completed (N=63) in less than nine monthsTopline results expected in 2Q27 with BLA to follow by ...

TalTech scientists in collaboration with researchers from Rockefeller University have described a mechanism that acts like a built-in clock in brain cell development, ensuring that the right genes ...

More than 60 years after its discovery, scientists are still learning surprising ways DNA stores and translates instructions ...

Abstract: In the analysis of gene expression time series, emphasis has been given on the capture of shape similarity (or dissimilarity). A number of proximity functions have been proposed for this ...

DNA stores the body’s operating playbook. Some genes encode proteins. Other sections change a cell’s behavior by regulating which genes are turned on or off. For yet others, the dark matter of the ...