👩‍🦰👨‍🦰Redheaded patients, due to a mutation in the MC1R gene, may experience unique, increased requirements for anesthesia and altered pain sensitivity. Evidence suggests they may need 20–30% more anesthetic. * Anesthesia Requirements: Studies indicate that people with natural red hair may require higher doses of volatile, subcutaneous, and intravenous anesthetic agents. * Pain Sensitivity: The mutated melanocortin-1 receptor (MC1R) gene, responsible for red hair, is part of a family involve

Mutations and selection