I prefer B12 shots as needed over a supplement that has to go through the digestive system for both horses and humans. I love IV therapy for myself, and when I was competing I had my vet Jug my horse often. For my trips back and forth from AZ to OK, we encounter a bunch of shifts in temperature, altitude, and weather patterns. I like giving some B12 to keep her feeling great. I also use it a couple of times a month for trigger point injections for nerve regeneration. Reminder... Always ask your